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Fig. 4 | BMC Cancer

Fig. 4

From: Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response

Fig. 4

Canonical pathway analysis of differentially expressed genes between CT-26 vs. Colon 26 from tumor tissues of different sizes and cell lines. CT-26 and Colon 26 tumors were compared at 3 different sizes to derive 3 sets of DE genes and the union of the 3 sets contained 4701 DE genes. Comparing CT-26 and Colon 26 cell lines revealed 4183 DE genes. A significant number of DE genes (2042, p < 1 × 10− 6, hypergeometric test) are shared between the tumor-tumor and cell line-cell line comparisons

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