Table 2 Univariate Cox regression analysis for overall survival (OS) and recurrence free survival (RFS) in 104 HCC patients

Age (≤ 60 vs. >  60 years)

1.206 (0.631–2.303)

0.571

0.989 (0.524–1.864)

0.972

Gender (males vs. females)

1.033 (0.454–2.352)

0.938

1.074 (0.495–2.334)

0.856

Pathological stage (high and/or middle vs. low)

3.819 (2.116–6.893)

< 0.001

3.172 (1.779–5.658)

< 0.001

Tumor diameter (≤ 5 vs. >  5 cm)

1.919 (1.000–3.681)

0.050

2.157 (1.152–4.039)

0.016

AFP (>  400 vs. <  400 ng/ml)

2.767 (1.305–5.868)

0.008

1.165 (0.621–2.186)

0.634

Child-Pugh grade (A vs. B)

1.848 (0.893–3.821)

0.098

0.899 (0.377–2.144)

0.810

Tumor Recurrence (yes vs. no)

3.894 (1.983–7.646)

< 0.001

–

–

CRBP-1 (high vs. low)

0.342 (0.150–0.784)

0.011

0.464 (0.226–0.955)

0.037