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Fig. 2 | BMC Cancer

Fig. 2

From: MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer

Fig. 2

miR-1915-3p suppresses the migration, invasion and EMT of NSCLC cells. A miR-1915-3p expression was analyzed by qRT-PCR in eleven lung cancer cell lines and a human normal bronchial epithelial cell line. B, C miR-1915-3p expression levels in miR-1915-3p/anti-miR-1915-3p-transfected A549 and H1975 cells. D, E Wound healing assay was carried out to determine cell migratory abilities in A549 and H1975 cells transfected with miR-NC, miR-1915-3p mimic, anti-miR-NC, or anti-miR-1915-3p. Relative wound width were presented in the histogram on the right. F, G Cell invasion assay was performed in transfected-A549 and H1975 cells as described in (D) (E). The number of invading cells per area was counted. Data represent the means±SEM from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bars, 100 μm. (H)(I) Western blot analysis of EMT markers in miR-1915-3p/anti-miR-1915-3p-transfected A549 and H1975 cells

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