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Table 2 Univariate and multivariate Cox regression analyses of SEC61G expression for survival of LUAD patients in TCGA dataset

From: Prognostic value of SEC61G in lung adenocarcinoma: a comprehensive study based on bioinformatics and in vitro validation

Characteristics

Total

Univariate analysis

Multivariate analysis

(N)

HR (95%CI)

P value

HR (95%CI)

P value

Gender (Male vs. Female)

497

0.954 (0.711 ~ 1.279)

0.752

  

Age (>70y vs. <=70y) T stage

487

1.464 (1.081 ~ 1.982)

0.014

1.493 (1.096 ~ 2.035)

0.011

(T2–4 vs. T1)

494

1.678 (1.187 ~ 2.373)

0.003

1.257 (0.873 ~ 1.812)

0.188

N stage (N1–3 vs. N0)

486

2.637 (1.957 ~ 3.553)

< 0.001

1.414 (0.865 ~ 2.314)

0.167

M stage (M1 vs. M0)

355

2.129 (1.243 ~ 3.648)

0.006

  

Pathologic stage (stage2–4 vs. stage1)

490

2.977 (2.184 ~ 4.058)

< 0.001

1.966 (1.164 ~ 3.319)

0.011

SEC61G (High vs. Low)

497

1.741 (1.296 ~ 2.388)

< 0.001

1.760 (1.297 ~ 2.388)

< 0.001

  1. HR hazard ratio, CI confidence interval