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Table 1 Clinicopathological characteristics of patients with SMIHigh and SMILow UGC

From: Impact of skeletal muscle mass in patients with unresectable gastric cancer who received palliative first-line chemotherapy based on 5-fluorouracil

 

All patients (n = 83)

SMIHigh (n = 41)

SMILow (n = 42)

p value

Age (years)

65.4 ± 12.4

64.9 ± 14.5

67.9 ± 9.2

0.176

Sex

   

0.119

 Male

61 (73.5)

27 (65.9)

34 (81.0)

 

 Female

22 (26.5)

14 (34.1)

8 (19.0)

 

ECOG PS (0/1/2)

   

0.209

 0

41 (49.4)

24 (58.5)

17 (40.5)

 

 1

38 (45.8)

16 (39.0)

22 (52.4)

 

 2

4 (4.8)

1 (2.5)

3 (7.1)

 

BMI

20.0 ± 3.8

21.5 ± 4.3

18.6 ± 2.5

< 0.001

SMI

42.8 ± 7.7

47.4 ± 7.3

38.2 ± 5.0

< 0.001

Unresectable cause

   

0.907

 Advanced cases

39 (47.0)

19 (46.3)

20 (47.6)

 

 Recurrent cases

44 (53.0)

22 (53.7)

22 (52.4)

 

Histologic type

   

0.222

 Differentiated

38 (45.8)

16 (39.0)

22 (52.4)

 

 Undifferentiated

45 (54.2)

25 (61.0)

20 (47.6)

 

Peritoneum metastases

   

0.903

 Positive

37 (44.6)

18 (43.9)

19 (45.2)

 

 Negative

46 (55.4)

23 (56.1)

23 (54.8)

 

Lymph node metastases

   

0.898

 Positive

35 (42.2)

17 (41.5)

18 (42.9)

 

 Negative

48 (57.8)

24 (58.5)

24 (57.1)

 

Hematogenous metastases

   

0.867

 Positive

25 (30.1)

12 (29.3)

13 (31.0)

 

 Negative

58 (69.9)

29 (70.7)

29 (69.0)

 

Lines of chemotherapy

   

0.289

  < 2nd line

16 (19.3)

6 (14.6)

10 (23.8)

 

 ≧2nd line

67 (80.7)

35 (85.4)

32 (76.2)

 

Lines of chemotherapy

    

  < 3rd line

42 (50.6)

16 (39.0)

26 (61.9)

0.037

 ≧3rd line

41 (49.4)

25 (61.0)

16 (38.1)

 
  1. Data are presented as mean ± standard deviation or number (percentage) of patients
  2. BMI, body mass index; ECOG PS, Eastern Cooperative Oncology Group performance status; SMI, skeletal muscle mass; SMIHigh, high skeletal muscle mass; SMILow, low skeletal muscle mass; UGC, unresectable gastric cancer