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Table 6 Comparison of PFS in patients receiving T-DM1 with or without prior treatment with taxane-trastuzumab-pertuzumab

From: Impact of the line of treatment on progression-free survival in patients treated with T-DM1 for metastatic breast cancer

Characteristics

No prior pertuzumab

n = 34

Prior pertuzumab

n = 17

Total

n = 51

Progression

 No

7 (20.6%)

3 (17.6%)

10 (19.60%)

 Yes

27 (79.4%)

14 (82.4%)

41 (80.4%)

PFS according to Kaplan-Meier (months)

 Median

9.50

3.55

9.01

 CI95

(6.15–12.26)

(2.27–11.38)

(4.87–11.41)

 Minimum

1.7

1.1

1.1

 Maximum

55.4

21.4

55.5

Intergroup comparison (Log-Rank test)

p-value

  

0.144