Fig. 4

Differential meta-analysis of total lipid expression in the non-recurrent and recurrent groups of the SQCC and AD cohorts. Total lipid intensity ratios in the recurrent groups showed a tendency for a slight decrease in the SQCC cohort (mean intensity ratio = 0.74) and a significant increase in the ADC cohort (mean intensity ratio = 1.41), demonstrating a significant inverse trend between the two histological types. Data are plotted as mean ± SD, along with individual data points. *P < 0.05, Welch’s t-test. Abbreviations: ADC, adenocarcinoma; n.s., not significant; SM, sphingomyelin; SQCC, squamous cell carcinoma