Fig. 1

Patient inclusion and exclusion flowchart. Figure 1. This figure illustrated the study design and patient selection process. We included men diagnosed with type 2 diabetes mellitus (T2DM), according to the National Diabetes Registry (NDR), amongst men included in Prostate Cancer data Base Sweden (PCBaSe) 4.1 in 2006–2016 and created two cohorts – “Prostate cancer (PCa) + Gonadotropin-releasing hormone agonists (GnRH) exposure cohort” and “GnRH exposure cohort”. 5714 men with PCa and 28,445 PCa-free men were included in the PCa + exposure cohort. The GnRH exposure cohort contained 692 PCa men who started GnRH after PCa diagnosis and 3460 PCa men not using GnRH as comparison