Fig. 7From: Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinomaThe activity of the ubiquitinated mutant Aurora A K143R is enhanced. A The mRNA expression of cell cycle-related downstream genes in ECa109 cells overexpressed Aurora A and Aurora A K143R was detected. B The mRNA expression of AP-2α-related downstream genes under Aurora A and Aurora A K143R overexpression was compared. C IκBα-NF-κB-related downstream genes mRNA expression was detected. D Overexpression of Aurora A and Aurora A K143R was performed to detect the expression of AKT-RAS-related downstream gene mRNA. E-F Compare the effects of Aurora A and Aurora A K143R on cell cycle changesBack to article page