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Fig. 3 | BMC Cancer

Fig. 3

From: Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Fig. 3

USP3 and Aurora A promote invasion and metastasis of ESCC cells. A-B ECa109 cells were plated in 6-well plates. After siRNA knocked out Aurora A and USP3, wound healing experiments were performed to observe the degree of scratch healing. C-D After overexpression of Flag-Aurora A and HA-USP3, wound healing experiments were performed to observe the degree of healing of the scratches. E-F ECa109 cells were plated in 6-well plates, and after knocking down Aurora A and USP3 with siRNA, transwell experiments were performed and the number of cells passing through transwell was counted. G-H After overexpression of Flag-Aurora A and HA-USP3, transwell experiments were performed and the number of cells passing through transwell was counted

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