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Table 1 Comparison of baseline clinical characteristics

From: Characteristics in gut microbiome is associated with chemotherapy-induced pneumonia in pediatric acute lymphoblastic leukemia

 

Affected group

Control group

P-value

(n = 14)

(n = 44)

Age [year, median (range)]

8.4 (3.0–15.0)

6.8 (3.0–14.0)

0.433

Male (n, %)

10 (71.4)

24 (54.5)

0.356

WBC [×109/L, median (range)]

51.8 (1.6–344.4)

13.2 (0.8–189.6)

0.001

Hemoglobin [g/L, median (range)]

86.9 (58.0–135.0)

86.0 (42.0–136.0)

0.353

Platelet [×109/L, median (range)]

58.6 (10.0–239.0)

97.3 (9.0–321.0)

0.061

blasts in BM (%)

85.6 (63.5–96.5)

71.8 (20.0–94.7)

0.017

CNS involvement (CNS2/3) (n, %)

2 (14.3)

3 (6.8)

0.585

Hepatosplenomegaly (n, %)

4 (28.6)

21 (47.7)

0.235

Swollen lymph nodes (n, %)

4 (28.6)

15 (34.1)

0.468

Immunophenotype

  

0.673

 B-ALL

11 (78.6)

38 (86.4)

 

 T-ALL

3 (21.4)

6 (13.6)

 

Risk Group

  

0.338

 low-risk (LR)

7 (50.0)

30 (68.2)

 

 intermediate-risk (IR)

7 (50.0)

14 (31.8)

 

Birth order

  

0.802

 first born (n, %)

10 (71.4)

29 (65.9)

 

 second child (n, %)

3 (21.4)

13 (29.5)

 

 third and upper (n, %)

1 (7.1)

2 (4.5)

 

Delivery

  

0.568

 spontaneous delivery

8 (57.1)

26 (59.1)

 

 caesarean section

6 (42.9)

18 (40.9)

 

Birth weight

  

0.513

 less than or equal to 3 kg (n, %)

3 (21.4)

15 (34.1)

 

 more than 3 kg (n, %)

11 (78.6)

29 (65.9)

 

Feeding patterns

  

0.711

 breastfeeding (n, %)

12 (85.7)

34 (77.3)

 

 non-breastfeeding (n, %)

2 (14.3)

10 (22.7)

 

Diet

  

0.676

 not picky eaters (n, %)

10 (71.4)

34 (77.3)

 

 meat-based (n, %)

3 (21.4)

9 (20.5)

 

 vegetarian-based (n, %)

1 (7.1)

1 (2.3)

 

Constipation (n, %)

3 (21.4)

6 (13.6)

0.673

BMI [kg/m2, median (range)]

31.0 (25.4–37.5)

26.8 (21.5–38.8)

0.152

  1. WBC White blood cell, CNS Central nervous system, BM bone marrow, BMI Body Mass Index