| Early (≤2 years) assessment |  | Late (> 2 years) assessment |  |
---|---|---|---|---|
Time Early effect coef/year | TT Early effect coef TT | Time Late effect coef/year | TT Late effect coef TT | |
Global health status | 11.3 * | −7.4 * | −0.9 | −5.7 |
C30 summary | 5.8 ** | −1.2 | −0.6 | 1.8 |
Physical functioning | 5.3 ° | 0.3 | −0.7 | −2.4 |
Role functioning | 25.0 *** | −4.5 | −1.3 | 5.0 |
Emotional functioning | 2.3 | 0.7 | −0.7 | 5.2 |
Cognitive functioning | 3.6 | 3.1 | −1.5 * | 15.9 *** |
Social functioning | 13.4 ** | −2.1 | −1.1 | −8.1 |
Fatigue free | 13.6 ** | −1.6 | −0.5 | 2.2 |
Pain free | 10.8 | −4.6 | −0.3 | −1.8 |
Dyspnea free | 4.8 | 0.8 | −1.1 | 8.9 * |