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Fig. 5 | BMC Cancer

Fig. 5

From: Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells

Fig. 5

Knockdown or overexpression of Dnmt3a in Jak2V617F BaF3 cells significantly affects cell proliferation capacity. A. Soft agar clone formation of Jak2V617F BaF3 cells; B. Soft agar clone formation of Dnmt3a-overexpressing Jak2V617F BaF3 cells; C. Soft agar clone formation of Dnmt3a-knockdown Jak2V617F BaF3 cells; D. Cell proliferation level of Jak2V617F BaF3 cells with Dnmt3a overexpression or with Dnmt3a knockdown

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