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Table 1 Pathologic and clinical data of patients from the Cancer Genome Atlas Project in Cutaneous Melanoma (TCGA-SKCM) according to the APC/CTNNB1 somatic mutation status. Abbreviations: * CTNNB1 copies/mean_cancer_ploidy_rounded_to_nearest_integer

From: The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma

  APC/CTNNB1 Mutant
N = 55
APC/CTNNB1 Wild type
N = 415
Age, at specimen procurement (years, median, range) 64 (37, 90) 61 (19, 90)
Breslow Depth, original diagnosis (mm, median, range) 2.85 (0.25, 15) 3 (0, 75)
Ulceration, original diagnosis (percent of specimens %) 39 55
Mitotic count rate, original diagnosis (mitoses/mm2, median, range) 4 (0, 33) 5 (0, 40)
Lymphocyte Score, procured specimen (1+ thru 6+ median, range) 2+ (0,6) 2+ (0, 6)
CTNNB1 gene copies* (median, range) 1 (0.5, 1.5) 1 (0.5, 3)
APC gene copies* (median, range) 1 (0.5, 2.5) 1 (0.33, 2.5)