From: The role of muscle depletion and visceral adiposity in HCC patients aged 65 and over undergoing TACE
 | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
 | HR (95% CI) | P value | HR (95% CI) | P value |
Age (year) | 1.060 (1.030–1.090) | < 0.001 | 1.057 (0.946–1.024) | < 0.001 |
Sex | 0.982 (0.726–1.330) | 0.905 |  |  |
BMI (kg/m2) | 0.983 (0.942–1.030) | 0.446 |  |  |
Diabetes | 1.170 (0.871–1.570) | 0.295 |  |  |
Hypertension | 0.759 (0.573–1.010) | 0.056 |  |  |
Cardiovascular attack | 1.330 (0.703–2.510) | 0.381 |  |  |
Other malignancy | 1.400 (0.810–2.410) | 0.229 |  |  |
Renal failure on dialysis | 1.920 (0.984–3.760) | 0.056 |  |  |
Alcohol | 0.937 (0.711–1.240) | 0.645 |  |  |
Smoking | 0.922 (0.700–1.220) | 0.565 |  |  |
Etiology | Â | 0.002 | Â | Â |
 Hepatitis B | 1 | – |  |  |
 Hepatitis C | 1.802 (1.295–2.507) | < 0.001 |  |  |
 Others | 1.314 (0.917–1.883) | 0.137 |  |  |
Variceal bleeding | 1.760 (0.437–7.110) | 0.426 |  |  |
Ascites | 1.910 (1.060–3.440) | 0.030 |  |  |
MELD score | 1.100 (1.050–1.160) | < 0.001 | 1.078 (0.928–1.009) | 0.027 |
Number of tumors | 1.250 (0.947–1.650) | 0.116 |  |  |
Size of tumor (cm) | 1.060 (1.020–1.110) | 0.006 | 1.083 (0.923–1.026) | 0.004 |
Albumin (g/dL) | 0.467 (0.358–0.611) | < 0.001 | 0.523 (1.912–0.383) | < 0.001 |
Platelet (uL) | 0.996 (0.993–0.999) | 0.004 | 0.996 (1.004–0.993) | 0.006 |
BCLC | Â | 0.022 | Â | 0.015 |
 stage 0 | 1 | – | 1 | – |
 stage A | 1.691 (1.012–2.824) | 0.045 | 1.711 (0.585–1.012) | 0.045 |
 stage B | 2.062 (1.221–3.480) | 0.007 | 2.003 (0.499–1.148) | 0.014 |
Infiltrative type of HCC | 1.210 (0.300–4.870) | 0.791 |  |  |
Serum AFP (ng/mL) | 1.000 (1.000–1.000) | 0.573 |  |  |
MDVA | 1.501 (1.118–2.014) | 0.007 | 1.515 (0.660–1.112) | 0.009 |
Objective tumor response | 0.614 (0.448–0.843) | 0.003 | 0.680 (1.471–0.488) | 0.023 |