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Table 3 Patients’ characteristics

From: Stereotactic body radiotherapy for intramedullary metastases: a retrospective series at the Oscar Lambret center and a systematic review

No. of patients

Age (years)

Sex

WHO*

Primary cancer

Mutations and Biomarkers

Concomitant systemic medication

Level

Presenting symptoms

Muscular strength at diagnosis

Use of corticosteroids

Time between diagnostic to start of SBRT (days)

1

67

M

2–3

Lung, adenocarcinoma

EGFR- / ALK-

PD-L1 70%

No

T10

Total paraplegia

0/5

No

14

2

69

F

1

Lung, adenocarcinoma

EGFR- / ALK- / KRAS-

No

T11

Posterior cord syndrome

4/5

No

21

3

72

M

2

Kidney, clear cell carcinoma

x

No

L2

Partial paraplegia

3/5

Yes (1 mg/kg)

6

4

33

M

0

Skin, melanoma

x

NIVOLUMAB

T8

None

5/5

No

33

5

62

F

1

Breast, adenocarcinoma

HER +++ / HR +

TRASTUZUMAB PERTUZUMAB

C4

None

5/5

Yes (1 mg/kg)

44

  1. *World Health Organization (WHO) at the diagnosis of metastasis
  2. Abbreviation: HR: Hormonal Receptors