Fig. 1

Normalization, filtration, and differential expression analysis for microarray profiles of GSE75271 dataset. (A) Dimensional distribution of expression matrix data after normalization. (B) Scree plot for dimensional distributions following normalization. (C) PCA for the classifications of normal and hepatoblastoma samples. (D) Volcano plot for up- and down-regulated genes between hepatoblastoma and normal samples. (E) Heat map for the expression of these genes in hepatoblastoma and normal samples