Item/Study | Li H et al | Wang D et al | Zhu L et al | Wu Z et al | Ours |
---|---|---|---|---|---|
PMID | 33,672,990 | 34,059,009 | 34,222,241 | 33,947,836 | NA |
Publishing date | 2021.02 | 2021.06 | 2021.07 | 2021.05 | NA |
FR gene set | 60 | 60 | 259 | 259 | 256 |
Species of FRGs | Human | Human | Human/Mice /Drosophila | Human/Mice /Drosophila | Human |
Risk signature | 8 | 9 | 11 | 15 | 8 |
Grouping criterion | Median | Median | Median | Median | Optimal cutoff value |
ROC (1Y/2Y/3Y) | None | 0.618/0.653/0.663 | 0.7/0.749/0.72 | 0.719 | 0.702 |
Validation cohorts | METABRIC (n = 1904) | GSE42568 ICGC (n = 154) | GSE20685 GSE20711 GSE42568 (n = 519) | None | METABRIC GSE20685 GSE58812 ICGC (n = 2248) |
Experiments in vitro | None | None | Alterations of FRGs expressions under Erastin inducing | None | SQLE biofunctions |
Data screening | None | Exclude samples follow up with 0 day | None | None | Exclude samples follow up less than 30 days |