Fig. 5From: Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancerThe effects of FR risk levels on TIM and the expressions of immune checkpoints. (A) The differences in infiltrating levels of 22 immune cells between high- and low-risk groups. High-risk group is red and low-risk group is green. (B-G) The correlations between FR risk score and the enrichments of six core immune cells. (H) The differences in activities of 11 immune signaling pathways between high- and low-risk groups. (I-N) The expressive correlations between FR risk score and six immune checkpoints. (H) The expressive differences of six immune checkpoints between high- and low-risk groups. FR, ferroptosis-related; TIM, tumor immune microenvironment; APC, antigen presentation cell; IFN, interferon; MHC, major histocompatibility complex; PD-1 (CD274), programmed cell death 1; * means P<0.05; ** means P<0.01; *** means P<0.001Back to article page