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Fig. 3 | BMC Cancer

Fig. 3

From: Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancer

Fig. 3

FR risk signature provides an important supplement to prognostic analysis of BC. (A) The result of cox univariate analysis in TCGA cohort. (B) The result of cox multivariate analysis in TCGA cohort. (C-L) FR risk signature can distinguish the prognostic differences of BC patients with most clinical subgroups. (M-P) The overall survival differences of patients with four molecular subtypes between high- and low-FR risk groups. (Q) The DCA of FR risk signature. Different curves represent four kinds of BC prognostic models based on multivariate logistic regression analysis. Model A represents the prognostic model composed of age and TNM stages. Model B represents the prognostic model composed age and clinical stage. Complex A represents the improved model A that added FR risk score. Complex B represents the improved model B that added FR risk score. (R) The nomogram composed of age, clinical stage, and FR risk score. (S-U) The calibration curves. FR, ferroptosis-related; BC, breast cancer; DCA, decision curve analysis

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BMC Cancer

ISSN: 1471-2407

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