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Table 4 Multivariable analysis showing the association of selected clinicopathologic characteristics with PTEN status

From: Combined analysis of PTEN, HER2, and hormone receptors status: remodeling breast cancer risk profiling

PTEN-WT vs. PTEN-L

 

OR

95% CI

p-value

Death

 Survived vs. Deceased

0.25

0.11–0.55

0.001

Grade

 1/2 vs. 3

0.853

0.62–1.18

0.329

HR and HER2 status

 HR+/HER2- vs. HR+/HER2+

0.78

0.4–1.51

0.451

 HR−/HER2- vs. HR+/HER2+

0.275

0.122–0.621

0.002

 HR−/HER2+ vs. HR+/HER2+

0.9

0.22–3.72

0.884

 HR−/HER2- vs. HR+/HER2-

0.36

0.21–0.61

< 0.0001

 HR−/HER2+ vs. HR+/HER2-

1.16

0.32–4.17

0.818

 HR−/HER2+ vs. HR−/HER2-

3.27

0.84–12.78

0.09

  1. PTEN-L PTEN low (i.e. decreased expression), PTEN-WT PTEN wild-type (i.e. retained expression), HR Hormone receptors, OR Odds ratio, CI Confidence interval
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BMC Cancer

ISSN: 1471-2407

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