Table 2 Correlation between low and wildtype status of PTEN across selected clinicopathologic features
| Â | PTEN-L | PTEN-WT | p-value |
|---|---|---|---|
All patients, n (%) | 280 (46.1) | 328 (53.9) | Â |
Age, mean (SD) | 61.5 (12.0) | 60.6 (13.6) | 0.3425 |
Histology, n (%) | |||
 Ductal | 224 (80.0) | 267 (81.4) | 0.6243 |
 Lobular | 40 (14.3) | 39 (11.9) |  |
 Other | 16 (5.7) | 22 (6.7) |  |
HR and HER2 status, n (%) | |||
 HR+/ HER2- | 213 (76.1) | 275 (83.8) | 0.0008 |
 HR−/ HER2+ | 4 (1.4) | 6 (1,8) |  |
 HR+/ HER2+ | 15 (5.4) | 25 (7.6) |  |
 HR−/ HER2- | 48 (17.1) | 22 (6.7) |  |
Grade, n (%) | |||
 1 | 34 (12.1) | 39 (11.9) | 0.6428 |
 2 | 116 (41.4) | 148 (45.1) |  |
 3 | 130 (46.4) | 141 (43.0) |  |
T, n (%) | |||
 1 | 180 (64.3) | 198 (60.4) | 0.7479 |
 2 | 83 (29.6) | 105 (32.0) |  |
 3 | 6 (2.1) | 8 (2.4) |  |
 4 | 11 (3.9) | 17 (5.2) |  |
N, n (%) | |||
 Positive | 164 (58.6) | 207 (63.1) | 0.2528 |
 Negative | 116 (41.4) | 121 (36.9) |  |
Stage, n (%) | |||
 0, 1 | 118 (42.1) | 154 (47.0) | 0.4682 |
 2 | 107 (38.2) | 112 (34.2) |  |
 3, 4 | 55 (19.6) | 62 (18.9) |  |