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Table 2 Characteristics of eligible studies for clinicopathological features

From: Clinicopathological features and prognostic significance of C5aR in human solid tumors: a Meta-analysis

Study

Year

Country

Tumor type

Samplesize

Male/Female

High/Low C5aR

Clinicopathologic Features

Zhao et al.

2018

China

NSCLC

185

128/57

104/81

Tumor size, Lymph node metastasis, TNM stage, Pathologic type

Kaida et al.

2016

Japan

GC

100

64/36

35/65

Tumor location, Differentiation, Depth of invasion, Lymph node metastasis, pStage, Lymphatic invasion, Vascular invasion

Hu et al.

2016

China

HCC

78

51/27

53/25

Tumor size, Tumor numbers, Capsular invasion, E-cadherin expression, Snail expression, Claudin-1 expression, Pathological grade, Tumor stage

Wada et al.

2016

Japan

UCC

52

39/13

38/14

Tumor location, WHO grade, T stage, Blood vessel invasion, Lymph node invasion, Stage of disease

Imamura et al.

2020

Japan

PC

161

NA

32/129

Gleason grade, Pathological Tstage, PD-L1 expression

Maeda et al.

2015

Japan

RCC

127

86/41

78/49

Histological subtypes, Fuhrman grade, TNM stage, microscopic invasion

Xi et al.

2016

China

RCC

272

188/84

141/131

Tumor size, Fuhrman grade, Necrosis, TNM stage, ECOG-PS

Nitta et al.

2016

Japan

GC

148

108/40

45/103

Tumor size, Location, Differentiation, Invasion depth, N classification, pStage, Lymphatic invasion, Vascular invasion, Amount of interstitial connective tissue, Infiltrative pattern

Imamura et al.

2015

Japan

BC

171

0/171

22/149

Menopause, Pathological tumor size, nuclear grade, Ki-67 labeling index, Nodular status, Clinical stages, Estrogen receptor (ER), Estrogen receptor (ER), HRE2, Tumor subtype

Gu et al.

2013

China

NSCLC

208

148/60

111/97

Smoking status, Histological type, Tumor stage, Lymph node metastasis, Tumor size, Differentiation

  1. NSCLC Non-small cell lung cancer, GC Gastric cancer, HCC Hepatocellular carcinoma, UCC Urothelial cell carcinoma, RCC Renal cell carcinoma, BC Breast cancer