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Table 4 The comparison of the main parameters of melanoma between the patients with (IS) and without (non-IS) immunosuppression

From: High regional mortality due to malignant melanoma in Eastern Finland may be explained by the increase in aggressive melanoma types

 

IS (142)

Non-IS (195)

p-value (IS versus non-IS)

Clark (data from 337 cases)

5

10.6%

6.7%

0.013

4

26.8%

16.4%

3

26.8%

23.1%

2

8.5%

16.4%

1

27.5%

37.4%

Breslow (337 cases)

4

15.5%

10.3%

0.018

3

17.6%

11.3%

2

16.9%

11.3%

1

50.0%

67.2%

Mitosis count (224 cases)

A lot

42.9%

32.5%

0.134

Little

42.9%

56.3%

No Mitosis

14.3%

11.1%

LV/BV/PN (103 cases)

Yes

2.5%

3.2%

0.843

No

97.5%

96.8%

Microsatellites (30 cases)

Yes

55.6%

33.3%

0.255

No

44.4%

66.7%

Ulceration (337 cases)

Yes

16.2%

14.4%

0.642

No

83.8%

85.6%

Growth type (337 cases)

4

6.3%

6.2%

0.238

3

40.8%

31.8%

2

24.6%

24.1%

1

28.2%

37.9%

Regression (335 cases)

Yes

7.1%

5.7%

0.596

No

92.9%

94.3%

Cell type (101 cases)

Epithelioid

14.3%

20.3%

0.790

Spindle cell

50.0%

39.0%

Nevoid

7.1%

6.8%

Mixed

23.8%

30.5%

Other

4.8%

3.4%

Recidivism (337 cases)

Yes

7.7%

4.6%

0.230

No

92.3%

95.4%

  1. LV/BV/PN = invasion into lymphatic/blood vessels or perineural area; growth type 1 = pure radial growth, 2 = radial growth with concomitant vertical growth, 3 = vertical growth with some concomitant radial growth and 4 = pure vertical growth