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Fig. 4 | BMC Cancer

Fig. 4

From: Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast cancer

Fig. 4

Principal component analysis (PCA) and hierarchical clustering heatmap of EV surface proteins detected by MACSPlex analysis. EV surface proteins detected by MACSPlex analysis in any of the patients were analyzed further using the bioinformatics software Qlucore. A-B) PCA illustrates the relationship between the technical replicates and variation between different patients were A shows connection between 1 nearest neighbor and B 3 nearest neighbors. C Hierarchical clustering heatmap of mean values for each patient. As illustrated by both PCA and heatmap, patient 2, 3, and 5 cluster together, and patient 1, 4, 6 and 7 cluster together

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