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Table 2 Univariate and multivariate survival analyses (proportional hazards method) for patients with primary HNSCC

From: Aberrant overexpression of transcription factor Forkhead box D1 predicts poor prognosis and promotes cancer progression in HNSCC

Parameters

Univariate survival analysis

Multivariate survival analysis

Hazard ratio

95% CI

P values

Hazard ratio

95% CI

P values

Gender(male, female)

1.527

0.691–3.374

0.296

1.969

0.665–5.830

0.221

Smoking(Yes, No)

1.484

0.591–3.727

0.401

1.473

0.308–7.049

0.628

Alcohol use (Yes, No)

0.681

0.282–1.643

0.392

0.428

0.118–1.551

0.196

Age (> 60, ≤60)

0.682

0.311–1.496

0.340

0.529

0.224–1.246

0.145

Tumor size (T3-T4, T1-T2)

0.747

0.312–1.792

0.514

0.842

0.329–2.158

0.720

Pathological grade (II-III, I)

0.622

0.213–1.813

0.384

0.645

0.188–2.221

0.487

Cervical nodal metastasis (N+, N0)

1.175

0.536–2.578

0.687

0.881

0.359–2.157

0.781

Clinical stage (III-IV, I-II)

1.558

0.685–3.545

0.290

1.272

0.517–3.13

0.600

FOXD1 expression (high, low)

4.159

1.626–10.641

0.003

4.926

1.728–14.045

0.003

  1. Bold indicates statistical significance, with P values less than 0.05