Fig. 5

The antitumor effects of BD0801, anti-PD-1 antibody, and anti-PD-L1 antibody in CT26 colorectal cancer syngeneic mouse model. (A-C) The CT26 tumor-bearing Balb/c mice received BD0801, anti-PD-1 antibody, anti-PD-L1 antibody, or different combinations by intraperitoneal injection biweekly (n = 10/group). G, Group. The error bars represent SEM. The P-value was calculated based on the tumor volume comparing to the assigned group using two-way ANOVA; treatment group versus vehicle group: **, P < 0.01; combination treatment group versus single treatment group: ##, P < 0.01. The tumor images are included in Supplementary Fig. S5