Table 4 Univariate and multivariate analysis of risk factors for progression-free survival

HR

95%CI

p

HR

95%CI

p

Age (years), </≥60

0.606

0.195–1.573

0.336

Sex, (male/female)

2.440

0.657–3.235

0.253

BMI, (kg/m²), </≥25

1.655

0.878–4.917

0.195

ECOG (0/1)

1.638

0.266–2.804

0.416

Hepatitis B, (yes/no)

2.434

0.632–4.161

0.685

Hepatitis C, (yes/no)

1.841

0.818–3.246

0.287

AFP (ng/ml), </≥400

1.565

1.124–3.027

0.011

2.917

1.425–4.760

0.002

Child-Pugh(A/B)

2.511

0.944–6.070

0.665

BCLC (yes/no)

2.628

0.606–3.649

0.705

Liver cirrhosis (yes/no)

1.298

0.428–2.822

0.691

PD-L1 expression

1.136

0.738–2.651

0.173

 Branch of portal vein

1.721

0.167–2.810

0.554

 Main portal vein

2.591

0.182–1.321

0.277

 Extrahepatic metastasis (yes/no)

1.782

0.441–3.647

0.287

 Number of metastatic sites (< 3/≥3)

2.368

0.375–3.458

0.748

 Treatment (PLH/PL)

1.779

1.281–2.680

0.002

2.315

1.211–3.629

0.001