Table 3 Univariate and multivariate analysis of risk factors for overall survival

HR

95%CI

p

HR

95%CI

p

Age (years), </≥60

1.185

1.305–2.129

0.747

Sex, (male/female)

0.583

0.392–2.470

0.274

BMI, (kg/m²), </≥25

1.191

0.726–1.103

0.125

ECOG (0/1)

1.182

0.943–2.734

0.282

Hepatitis B, (yes/no)

1.688

0.769–2.650

0.511

Hepatitis C, (yes/no)

1.352

0.144–2.013

0.206

AFP (ng/ml), </≥400

1.566

0.072–2.317

0.114

Child-Pugh (A/B)

2.403

2.500–8.434

0.005

2.633

1.391–9.648

0.001

BCLC (B/C)

1.390

0.651–2.591

0.171

Liver cirrhosis (yes/no)

1.772

0.785–3.647

0.663

PD-L1 expression

1.473

0.860–3.429

0.052

Tumor thrombus

Absent

Branch of portal vein

1.583

0.303–4.752

0.545

Main portal vein

1.276

0.295–6.298

0.901

Extrahepatic metastasis (yes/no)

1.292

0.747–3.842

0.118

Number of metastatic sites (< 3/≥3)

2.104

1.360–4.476

0.007

2.193

1.187–4.366

0.002

Treatment (PLH/PL)

2.499

1.726–4.902

0.005

3.649

1.592–6.074

0.001