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Table 3 Follow-up workflow

From: POstmastectomy radioThErapy in Node-posiTive breast cancer with or without Internal mAmmary nodaL irradiation (POTENTIAL): a study protocol for a multicenter prospective phase III randomized controlled trial

 

Pre-RT

During RT

6 months after RT

6 months to 5 years after RT

5–10 years after RT

baseline

weekly

end

1 week

2 weeks

3 months

6 months

every 6 months

annually

History and physical exam

X

X

X

X

X

X

X

X

X

Complete blood cell count

X

X

X

X

X

X

X

X

X

Thyroid function (Blood analysis)

X

    

X

X

X

X

†Myocardial enzyme spectrum

X

    

X

X

X

X

Chest CT

X

    

X

X

X

X

Regional nodal ultrasonography

X

    

X

X

X

X

Ultrasonography/CT/MRI for liver

X

    

X

X

X

X

Twelve-lead electrocardiogram

X

    

X

X

X

X

Echocardiography

X

    

X

X

X

X

†‡Coronary CT angiography

X

      

(1) 3 years

6, 10 years

Quality of life

X

 

X

  

X

X

X

 
  1. † Applicable to patients for whom the examination is accessible
  2. ‡ The frequency of coronary CT angiography examination is dependent on patient age and the baseline status of coronary artery stenosis. For patients younger than 65 years and with less than 50% stenosis in left anterior descending coronary artery (LAD), left circumflex artery (LCX) and right coronary artery (RCA), the coronary CT angiography examination is scheduled at 3, 6, and 10 years after RT. If the stenosis severity in one of the three main coronary arteries exceeds 50% and/or the patient is older than 65 years, the coronary CT angiography examination is scheduled at 1, 3, 6, and 10 years after RT. If the stenosis severity in one of the three main coronary arteries exceeds 75%, revascularization should be performed and the coronary CT angiography examination is scheduled at 3, 6, and 10 years after RT
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