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Table 2 The association of HBV infection with the risk of CRC among different regressions

From: Associations between hepatitis B virus infection and risk of colorectal Cancer: a population-based prospective study

  HBsAg Seronegative HBsAg Seropositive Adjusted Hazard Ratios
(95% CI)
Cases Person-years Cases Person-years
Multivariate COX Regression
Model 1 430 1,042,506 18 28,617 1.52(0.95 ~ 2.44)
Model 2 430 1,042,506 18 28,617 1.79(1.12 ~ 2.87)
Model 3 430 1,042,506 18 28,617 1.85(1.15 ~ 2.96)
SD Model
Model 1 430 1,042,506 18 28,617 1.47(0.92 ~ 2.36)
Model 2 430 1,042,506 18 28,617 1.71(1.07 ~ 2.74)
Model 3 430 1,042,506 18 28,617 1.77(1.11 ~ 2.84)
CS Model
Model 1 430 1,042,506 18 28,617 1.50(0.94 ~ 2.40)
Model 2 430 1,042,506 18 28,617 1.74(1.11 ~ 2.78)
Model 3 430 1,042,506 18 28,617 1.79(1.13 ~ 2.91)
  1. Note:
  2. Model 1: Univariate analysis
  3. Model 2: Adjusted for age (every 10 years), sex based on model 1
  4. Model 3: Further adjusted for BMI (normal, overweight, obesity), hypercholesterolemia, hypertriglyceridemia, hs-CRP (< 1 mg/L, 1–3 mg/L, > 3 mg/L), hyperbilirubinemia, elevated alanine aminotransferase, diabetes, family income, educational background, marital status, salt consumption, current smoker, drinking status, physical activity and family history of cancer based on model 2
  5. CS model Cause-specific hazard model, SD model Sub-distribution hazard function model