Skip to main content

Table 3 Clinicopathological characteristics according to the level of γ-GT

From: Exploring the clinical value of preoperative serum gamma-glutamyl transferase levels in the management of patients with hepatocellular carcinoma receiving postoperative adjuvant transarterial chemoembolization

Characteristic γ-GT ≤ 54 U/L
(n = 947)
γ-GT > 54 U/L
(n = 900)
P-value
Age (years) Mean ± SD 52.3 (10.5) 52.1 (10.6) 0.778
Sex Female 182 (19.2%) 90 (10.0%) < 0.001
  Male 765 (80.8%) 810 (90.0%)  
HBV infection No 139 (14.7%) 103 (11.4%) 0.047
  Yes 808 (85.3%) 797 (88.6%)  
Cirrhosis No 315 (33.3%) 295 (32.8%) 0.863
  Yes 632 (66.7%) 605 (67.2%)  
TBil (μmol/L) Mean ± SD 14.2 (5.54) 15.1 (6.78) 0.003
Child-pugh A 925 (97.7%) 826 (91.8%) < 0.001
  B 22 (2.3%) 74 (8.2%)  
AFP (ng/mL) ≤400 662 (69.9%) 593 (65.9%) 0.072
  > 400 285 (30.1%) 307 (34.1%)  
Transfusion No 926 (97.8%) 813 (90.3%) < 0.001
  Yes 21 (2.2%) 87 (9.7%)  
Tumor number Single 799 (84.4%) 700 (77.8%) < 0.001
  Multiple 148 (15.6%) 200 (22.2%)  
Tumor diameter (cm) Mean ± SD 4.60 (2.64) 7.17 (4.33) < 0.001
ES grading I/II 99 (10.5%) 73 (8.1%) 0.097
  III/IV 848 (89.5%) 827 (91.9%)  
Capsule Present 770 (81.3%) 717 (79.7%) 0.405
  Absent 177 (18.7%) 183 (20.3%)  
Satellite No 572 (60.4%) 499 (55.4%) 0.035
  Yes 375 (39.6%) 401 (44.6%)  
MVI Present 311 (32.8%) 333 (37.0%) 0.068
  Absent 636 (67.2%) 567 (63.0%)  
BCLC 0 79 (8.3%) 28 (3.1%) < 0.001
  A 755 (79.8%) 691 (76.8%)  
  B 113 (11.9%) 181 (20.1%)  
AJCC Ia 79 (8.3%) 28 (3.1%) < 0.001
  Ib 495 (52.3%) 443 (49.2%)  
  II 322 (34.0%) 301 (33.4%)  
  IIIa 51 (5.4%) 128 (14.2%)  
CNLC Ia 549 (58.0%) 297 (33.0%) < 0.001
  Ib 285 (30.1%) 422 (46.9%)  
  IIa 90 (9.5%) 113 (12.6%)  
  IIb 23 (2.4%) 68 (7.6%)  
PA-TACE No 707 (74.7%) 628 (69.8%) 0.022
  Yes 240 (25.3%) 272 (30.2%)  
  1. Note: HBV hepatitis B virus, TBil total bilirubin; AFP alpha-fetoprotein; γ-GT gamma-glutamyl transferase; ES Edmondson-Steiner; MVI microvascular invasion; PA-TACE postoperative adjuvant transarterial chemoembolization; AJCC according to the 8th American joint committee on cancer staging; CNLC CNLC staging was defined according the Chinese guideline for HCC