Table 3 Clinicopathological characteristics according to the level of γ-GT
Characteristic | γ-GT ≤ 54 U/L (n = 947) | γ-GT > 54 U/L (n = 900) | P-value | |
|---|---|---|---|---|
Age (years) | Mean ± SD | 52.3 (10.5) | 52.1 (10.6) | 0.778 |
Sex | Female | 182 (19.2%) | 90 (10.0%) | < 0.001 |
Male | 765 (80.8%) | 810 (90.0%) | ||
HBV infection | No | 139 (14.7%) | 103 (11.4%) | 0.047 |
Yes | 808 (85.3%) | 797 (88.6%) | ||
Cirrhosis | No | 315 (33.3%) | 295 (32.8%) | 0.863 |
Yes | 632 (66.7%) | 605 (67.2%) | ||
TBil (μmol/L) | Mean ± SD | 14.2 (5.54) | 15.1 (6.78) | 0.003 |
Child-pugh | A | 925 (97.7%) | 826 (91.8%) | < 0.001 |
B | 22 (2.3%) | 74 (8.2%) | ||
AFP (ng/mL) | ≤400 | 662 (69.9%) | 593 (65.9%) | 0.072 |
> 400 | 285 (30.1%) | 307 (34.1%) | ||
Transfusion | No | 926 (97.8%) | 813 (90.3%) | < 0.001 |
Yes | 21 (2.2%) | 87 (9.7%) | ||
Tumor number | Single | 799 (84.4%) | 700 (77.8%) | < 0.001 |
Multiple | 148 (15.6%) | 200 (22.2%) | ||
Tumor diameter (cm) | Mean ± SD | 4.60 (2.64) | 7.17 (4.33) | < 0.001 |
ES grading | I/II | 99 (10.5%) | 73 (8.1%) | 0.097 |
III/IV | 848 (89.5%) | 827 (91.9%) | ||
Capsule | Present | 770 (81.3%) | 717 (79.7%) | 0.405 |
Absent | 177 (18.7%) | 183 (20.3%) | ||
Satellite | No | 572 (60.4%) | 499 (55.4%) | 0.035 |
Yes | 375 (39.6%) | 401 (44.6%) | ||
MVI | Present | 311 (32.8%) | 333 (37.0%) | 0.068 |
Absent | 636 (67.2%) | 567 (63.0%) | ||
BCLC | 0 | 79 (8.3%) | 28 (3.1%) | < 0.001 |
A | 755 (79.8%) | 691 (76.8%) | ||
B | 113 (11.9%) | 181 (20.1%) | ||
AJCC | Ia | 79 (8.3%) | 28 (3.1%) | < 0.001 |
Ib | 495 (52.3%) | 443 (49.2%) | ||
II | 322 (34.0%) | 301 (33.4%) | ||
IIIa | 51 (5.4%) | 128 (14.2%) | ||
CNLC | Ia | 549 (58.0%) | 297 (33.0%) | < 0.001 |
Ib | 285 (30.1%) | 422 (46.9%) | ||
IIa | 90 (9.5%) | 113 (12.6%) | ||
IIb | 23 (2.4%) | 68 (7.6%) | ||
PA-TACE | No | 707 (74.7%) | 628 (69.8%) | 0.022 |
Yes | 240 (25.3%) | 272 (30.2%) | ||