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Table 4 Odds ratio (95% CI) of advanced stage of disease at diagnosis in 1074 children

From: Socioeconomic position and prediagnostic health care contacts in children with cancer in Denmark: a nationwide register study

 

Advanced stage

Low stage

Model 1a

Model 2b

B-cell acute lymphoblastic leukemiac (N = 601)

 Highest parental education in household

  Long

20

270

1 (Ref.)

1 (Ref.)

  Medium

18

233

1.07 (0.55–2.08)

1.09 (0.56–2.13)

  Short

5

55

1.01 (0.35–2.92)

1.07 (0.37–3.08)

 Household cohabitation status

  Parents as couple

31

480

1 (Ref.)

1 (Ref.)

  Single parent

12

78

2.39 (1.14–4.99)

2.36 (1.13–4.95)

 Depression in household parents

  No

NA

503

1 (Ref.)

1 (Ref.)

  Yes

NA

55

0.64 (0.19–2.15)

0.68 (0.20–2.30)

T-cell acute lymphoblastic leukemiac (N = 98)

 Highest parental education in household

  Long

19

21

1 (Ref.)

1 (Ref.)

  Medium

20

27

0.83 (0.35–1.96)

0.84 (0.35–1.98)

  Short

5

6

0.86 (0.22–3.35)

0.92 (0.24–3.60)

 Household cohabitation status

  Parents as couple

38

46

1 (Ref.)

1 (Ref.)

  Single parent

6

8

0.99 (0.31–3.19)

0.98 (0.30–3.18)

 Depression in household parents

  No

37

44

 

1 (Ref.)

 Yes

7

10

0.89 (0.30–2.62)

0.85 (0.29–2.51)

Hodgkin lymphomad (N = 89)

 Highest parental education in household

  Long

NA

30

1 (Ref.)

1 (Ref.)

  Medium

NA

24

1.42 (0.57–3.53)

1.60 (0.63–4.03)

  Short

NA

4

0.45 (0.04–4.46)

0.52 (0.05–5.21)

 Household cohabitation status

  Parents as couple

26

49

1 (Ref.)

1 (Ref.)

  Single parent

5

9

1.17 (0.35–3.93)

1.13 (0.34–3.78)

 Depression in household parents

  No

26

53

1 (Ref.)

1 (Ref.)

  Yes

5

5

1.80 (0.46–7.00)

1.98 (0.50–7.78)

Non-Hodgkin and Burkitt lymphomad (N = 98)

 Highest parental education in household

  Long

34

NA

1 (Ref.)

1 (Ref.)

  Medium

20

NA

0.32 (0.13–0.81)

0.34 (0.13–0.85)

  Short

11

NA

3.82 (0.44–33.29)

3.95 (0.45–34.50)

 Household cohabitation status

  Parents as couple

53

26

1 (Ref.)

1 (Ref.)

  Single parent

12

7

0.85 (0.29–2.45)

0.86 (0.30–2.48)

 Depression in household parents

  No

57

27

1 (Ref.)

1 (Ref.)

  Yes

8

6

0.66 (0.20–2.12)

0.64 (0.20–2.08)

Ewing’s sarcomae(N = 86)

 Highest parental education in household

  Long

NA

30

1 (Ref.)

1 (Ref.)

  Medium

NA

23

1.86 (0.68–5.08)

1.91 (0.70–5.24)

  Short

NA

9

0.27 (0.03–2.48)

0.28 (0.03–2.57)

 Household cohabitation status

  Parents as couple

20

50

1 (Ref.)

1 (Ref.)

  Single parent

4

12

0.76 (0.21–2.71)

0.75 (0.21–2.68)

 Depression in household parents

  No

20

53

1 (Ref.)

1 (Ref.)

  Yes

4

9

1.15 (0.31–4.28)

1.26 (0.34–4.75)

Osteosarcomae (N = 62)

 Highest parental education in household

  Long

NA

19

1 (Ref.)

1 (Ref.)

  Medium

NA

22

1.66 (0.43–6.49)

1.68 (0.43–6.57)

  Short

NA

6

2.25 (0.37–13.58)

2.36 (0.39–14.32)

 Household cohabitation status

  Parents as couple

11

39

1 (Ref.)

1 (Ref.)

  Single parent

4

8

1.86 (0.46–7.53)

1.86 (0.46–7.58)

 Depression in household parents

  No

NA

38

1 (Ref.)

1 (Ref.)

  Yes

NA

9

0.72 (0.13–3.82)

0.70 (0.13–3.76)

Rhabdomyosarcomae (N = 40)

 Highest parental education in household

  Long

NA

NA

1 (Ref.)

1 (Ref.)

  Medium

NA

NA

0.33 (0.03–3.23)

0.35 (0.04–3.49)

  Short

NA

NA

2.04 (0.24–17.03)

2.16 (0.25–18.41)

  1. aModel 1 is adjusted for sex, diagnosis period and diagnosis age (as a continuous variable), highest parental education in the household and household cohabitation status.
  2. bModel 2 is adjusted for sex, diagnosis period and diagnosis age (as a continuous variable), highest parental education in the household, household cohabitation status, and additionally adjusted for number of total contacts in the last 24 months before diagnosis (as a continuous variable).
  3. cAdvanced stage: WBC at diagnosis ≥100 × 109/L; Low stage: WBC at diagnosis < 100 × 109/L
  4. dAdvanced stage: Stage 3–4; Low stage: Stage 1–2; eAdvanced stage: Metastases; Low stage: No distant metastases/unknown. For rhabdomyosarcoma, few observations in analyses of cohabitation status and depression, resulted in too uncertain estimates and are not shown
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BMC Cancer

ISSN: 1471-2407

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