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Fig. 7 | BMC Cancer

Fig. 7

From: LncRNA LINC00342 promotes gastric cancer progression by targeting the miR-545-5p/CNPY2 axis

Fig. 7

Knockdown of LINC003421 efficiently suppressed the tumorigenesis of GC by regulating miR-545-5p/CNPY2 axis in vivo. The tumor model was established by the subcutaneous inoculation with stably sh-LINC00342–1 or sh-NC transfected AGS cells. A The expression of LINC00342 in tumor tissues was evaluated by qRT-PCR. B The representative images of tumors in two groups. C Tumor volume. D Tumor weight. E The expression of miR-545-5p and CNPY2 in tumor tissues was evaluated by qRT-PCR. F The expression of CNPY2 in tumor tissues was evaluated by western blot. G Cell proliferation in tumor tissues was evaluated by IHC assay using anti-Ki67 antibody. × 200 magnification, scale bar = 100 μm. Gray color: Ki67; Blue color: nuclei. * p < 0.05, ** p < 0.01 vs sh-NC

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