Table 4 Time-dependent multivariate analysis of the prognostic factors for patients with GISTs
Hazard ratio | p | |
|---|---|---|
At Surgery | ||
Age | 0.013 | |
≥ 50 | 1·00 (reference) | |
<50 | 2.31 (1.20,4.44) | |
Sex | 0.031 | |
Female | 1·00 (reference) | |
Male | 2.00 (1.07,3.76) | |
Tumor size, cm | 0.152 | |
< 5.0 | 1·00 (reference) | |
≥ 5.0 | 1.69 (0.83,3.46) | |
Tumor location | 0.259 | |
Gastric | 1·00 (reference) | |
Nongastric | 1.42 (0.77,2.62) | |
Mitotic Index, per 50 HPFs | 0.014 | |
≤ 5.0 | 1·00 (reference) | |
>5.0 | 2.10 (1.17,3.78) | |
Tumor rupture | 0.046 | |
No | 1·00 (reference) | |
Yes | 2.41 (1.02,5.71) | |
1 yr | ||
Age | 0.025 | |
≥ 50 | 1·00 (reference) | |
<50 | 2.17 (1.10,4.26) | |
Sex | 0.042 | |
Female | 1·00 (reference) | |
Male | 1.93 (1.02,3.64) | |
Mitotic Index, per 50 HPFs | 0.005 | |
≤ 5.0 | 1·00 (reference) | |
>5.0 | 2.34 (1.29,4.25) | |
3 yr | ||
Sex | 0.042 | |
Female | 1·00 (reference) | |
Male | 1.93 (1.02,3.64) | |
Mitotic Index, per 50 HPFs | 0.005 | |
≤ 5.0 | 1·00 (reference) | |
>5.0 | 2.34 (1.29,4.25) | |
5 yr | ||
Mitotic Index, per 50 HPFs | 0.023 | |
≤ 5.0 | 1·00 (reference) | |
>5.0 | 3.25 (1.17,8.97) | |
6 yr | ||
None | ||