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Table 1 LncRNAs significantly associated with the disease free survival in the training cohort patients (N = 150)

From: Identification and characterization of a 25-lncRNA prognostic signature for early recurrence in hepatocellular carcinoma

Ensembl

Gene Symbol

P value a

Hazard Ratio a

Coefficient b

associated diseases

Description

Reference

ENSG00000253417

LINC02159

< 0.001

2.85

0.069

colorectal cancer, melanoma, head and neck squamous cell carcinoma

long intergenic non-protein coding RNA 2159

[1,2,3]

ENSG00000272205

 

< 0.001

2.47

0.233

NR

NR

 

ENSG00000269894

 

< 0.001

2.48

0.092

NR

NR

 

ENSG00000275437

 

< 0.001

4.78

0.083

NR

NR

 

ENSG00000223392

CLDN10-AS1

< 0.001

1.82

0.278

atherogenesis, lung adenocarcinoma, colorectal cancer, thyroid cancer, cholangiocarcinoma, colon adenocarcinoma

CLDN10 antisense RNA 1

[4,5,6, 20]

ENSG00000248596

LOC643201

< 0.001

1.91

0.335

colorectal cancer

centrosomal protein 192 kDa pseudogene

[5]

ENSG00000268201

 

< 0.001

1.98

0.330

NR

NR

 

ENSG00000247675

LRP4-AS1

< 0.001

7.36

0.567

breast cancer, pancreatic neuroendocrine tumour

LRP4 antisense RNA 1

[7]

ENSG00000231918

LOC730100

< 0.001

2.19

0.339

glioma

uncharacterized LOC730100

[8]

ENSG00000259834

 

< 0.001

0.28

−0.721

NR

NR

 

ENSG00000234129

 

0.001

9.68

0.272

NR

NR

 

ENSG00000269974

 

0.001

2.24

0.007

NR

NR

 

ENSG00000254887

LOC100505622

0.002

0.05

−0.735

gastric cancer

uncharacterized LOC100505622

[12]

ENSG00000259974

LINC00261

0.003

0.69

− 0.187

hepatocellular carcinoma, endometrial carcinoma, non-small cell lung cancer, colon cancer, esiohageal cancer, endometriosis, choriocarcinoma, gastric cancer, esophageal cancer, lung epithelial homeostasis, endoderm differentiation

long intergenic non-protein coding RNA 261

[13,14,15,16,17,18,19, 25,26,27]

ENSG00000236366

LOC153910

0.003

1.65

0.232

lung function development, chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD)

uncharacterized LOC153910

[3, 21,22,23,24]

ENSG00000275223

 

0.003

1.56

0.024

NR

NR

 

ENSG00000253406

 

0.004

967.38

1.878

NR

NR

 

ENSG00000232079

LINC01697

0.009

1.53

0.142

lung squamous cell carcinoma, gastric cancer, gastric adenocarcinoma, breast cancer

long intergenic non-protein coding RNA 1697

[9,10,11]

ENSG00000273837

 

0.012

0.59

−0.025

NR

NR

 

ENSG00000255980

LOC102724265

0.017

10.02

0.125

NR

uncharacterized LOC102724265

 

ENSG00000267905

 

0.018

1.5

0.032

NR

NR

 

ENSG00000176912

TYMSOS

0.023

1.28

0.038

NR

TYMS opposite strand

 

ENSG00000254333

NDST1-AS1

0.032

1.21

0.044

NR

NDST1 antisense RNA 1

 

ENSG00000231246

LINC02884

0.033

0.17

−0.041

NR

long intergenic non-protein coding RNA 2884

 

ENSG00000234283

 

0.047

0.39

−0.459

NR

NR

 
  1. NR not reported
  2. a Derived from the univariable Cox proportional hazards regression analysis in the 150 training cohort patients
  3. b Derived from the LASSO regression analysis in the 150 training cohort patients
  4. Please refer to the supplementary material for references citation