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Table 2 Univariate and multivariate analyses of the overall survival in patients with ccRCC

From: Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma

Parameters Univariate analysis C3 - Multivariate analysis FN1 - Multivariate analysis
P-value HR 95% CI (lower/upper) P-value HR 95% CI (lower/upper) P-value HR 95% CI (lower/upper)
Age <0.001 1.775 1.307 2.410 0.001 1.714 1.259 2.333 <0.001 1.759 1.292 2.394
> 60 vs ≤60
Female vs. male 0.711 1.060 0.779 1.442         
Clinical stage <0.001 3.839 2.800 5.264 0.013 2.377 1.200 4.711 0.006 2.591 1.306 5.144
III/IV vs I/II
Pathologic T <0.001 3.156 2.333 4.269 0.891 0.959 0.529 1.739 0.701 0.889 0.488 1.619
T3/T4 vs T1/T2
Pathologic N <0.001 3.857 2.089 7.124 0.027 2.049 1.085 3.871 0.036 1.980 1.044 3.755
N1 vs N0
Pathologic M <0.001 4.387 3.222 5.973 <0.001 2.454 1.692 3.558 <0.001 2.372 1.635 3.442
M1 vs M0
C3 expression 0.001 1.900 1.321 2.731 0.032 1.498 1.036 2.166     
High vs low     
FN1 expression <0.001 1.695 1.256 2.288      0.009 1.512 1.110 2.058
High vs low     
  1. Abbreviations: ccRCC clear cell renal cell carcinoma, HR hazard ratio, CI confidence interval; Significant associations are shown in bold face in the P-value column (P < 0.05)