Fig. 6

Comparison of candidate gene expression levels in different clinicopathological groups, survival analysis, and GESA analysis. Comparison of C3, FN1, and C3AR1 expression levels in groups of different (A) overall cancer stage, (B) histological grade (G), and (C) tumor size (T). Kaplan-Meier plots for (D) overall survival analysis and (E) recurrence-free survival analyses of the three genes in ccRCC based on the Kaplan-Meier plot in TCGA-KIRC dataset. (F) Representative signaling pathways significantly enriched in C3, FN1, and C3AR1 overexpression phenotypes determined by GSEA