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Fig. 5 | BMC Cancer

Fig. 5

From: Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma

Fig. 5

Validation of candidate gene expression levels at the transcriptional and translational levels. (A) C3, FN1, and C3AR1 mRNA expression in various normal human tissues and cancer tissues. (B) Comparison of C3, FN1, and C3AR1 mRNA expression levels in ccRCC tissues (n = 539) and normal renal tissues (n = 72). (C) Comparison of C3, FN1, and C3AR1 mRNA expression levels in 72 paired ccRCC tissues. (D) Comparison of C3 and FN1 protein expression levels in ccRCC tissues (n = 110) and normal renal tissues (n = 84). (E) Comparison of C3 and FN1 protein expression levels in 84 paired ccRCC tissues. (F) Representative IHC staining images of C3 and FN1 in normal kidney tissues and ccRCC tissues. *P < 0.05, **P < 0.01, ***P < 0.001

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