Fig. 4

Comparison of methylation according to histology, tumor stages and mutation status. Comparison of the methylation of WIF1 and NPY genes according to A) the histology of the tumor (ADC-WD or ADC-PD). Non-parametric Mann-Withney test. B) Tumor stage (stage I and II, III or IV). Non-parametric Kruskal-Wallis test. C) The mutated or non-mutated status of the tumor. Non-parametric Mann-Whitney test. D) Tumor tissues compared to the adjacent healthy tissues. Non-parametric Mann-Withney test in paired series. ADC-WD: well-differentiated adenocarcinoma, ADC-PD: partially differentiated adenocarcinoma