Fig. 3

a All eight scores were significantly higher in the TP53 mutated tumors compared with the TP53 wild type tumors in the genome-wide analysis. The box plot shows the genome-wide scores for the TP53-mutated tumors (blue) and the TP53 wild type tumors (pink) for all eight indices. The p-values (−log10) from the comparison analyses are shown above each column and a value > 2 was considered as significant after multiple testing corrections. b The arm-wise scores at chromosome arm 17p showing the eight indices for the TP53 wild type tumors at the left and the TP53 mutated tumors at the right. The scores for each sample are colored by intensity. The p-values (−log10) from the comparison analyses are shown above each column and a value > 3 was considered as significant after multiple testing corrections