Study information Country | Screening procedure | Recruitment & sampling | Reminder | Education provided as part of intervention | Intervention timeframe | Participants | Screening uptake/ participation (%) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HRFQ/ RA | FOBT/FIT | Colonoscopya | Who recruited participants | Sampling | Face-to-face | Phone | Letter/ e-mail | Media | Where recruited | HRFQ | FOBT/ FIT | Colonoscopy | |||||
Stool test uptake > 65% | |||||||||||||||||
Cai et al 2011 Ma et al 2012 China | x | 2 x FIT 1 x FOBT | If + | Unclear (likely led by physician) | Population-based | x | – | – | – | C | – | – | 2007–2009 | Residents aged 40–74 y. (medically & economically underserved) Enrolled n = 31,963 | 84.6 | 76.2 (1 x FIT) 65.3 (2 x FIT) | 78.7 |
Gong et al. 2018 [5] China | x | 2 x FIT | If + | CHC staff | Population -based | (x) | – | – | x | C | x | – | Jan – Dec 2013 | Residents aged 50–74 y. Registered n = 809,528 | 97.7 | 97.7 | 39.8 |
Zheng et al 2003 [10] China | x | 1 x RPHA- FOBT | Sigmoidoscopy if + | Field interviewers | Population-based | x | – | – | – | C | – | – | Data used from 1989 to 1996 | Residents aged ≥30 y. Recruited n = 75,813/192,261 eligible residents (39.4%) RPHA-FOBT & Risk assessment: 82.7% | 82.7 | 82.7 | 73.6 |
Hassan et al. 2016 [12] Malaysia | – | 1 x FIT, 2nd if negative) | If + | Physician | Purposive sampling | x | – | – | – | CHC/ H | – | – | 2013 | Patients who underwent iFOBT in 2013 aged ≥50 y. Enrolled n = 750 | – | R1: 94.7 R2: 90.6 | 68.1 |
Noriah et al. 2010 [13] Malaysia | – | 1 x FOBT | If + | Health care workers/ media | IG1: Random sampling IG2: Voluntary Response sampling IG3: Convenience sampling | IG1 & IG 3 | – | – | IG2 | C CHC | – | – | 15th Sept – 31st Dec 2007 | Adults aged ≥50 y. 605/2574 participants IG1 & IG 2: residents IG3: patients IG1 n = 151 (86.6%) IG2 n = 275 (13.8%) IG3 n = 179 (44.8%) | – | IG1: 95.4 IG2: 87.6 IG3: 92.2 | Unclear |
Tze et al. 2016 [14] Malaysia | – | 1 x FIT | If + | Volunteer -medical students (with support from community leaders) | Convenience sampling | x | – | – | – | C | – | Awareness Workshops (group) | 2010–2015 (1-y project in 5 different district every year) | Residents aged ≥50 y. 1581 FIT kits were distributed | – | 80–100% (varied by year) | 63.2–78.6 |
Aniwan et al. 2017 [16] Thailand | – | 1 x FIT | 1 x | Unclear (likely led by nurses) | Convenience sampling | x | – | – | – | H | – | – | Dec 2014 – Dec 2016 | Participants from 6 hospitals across Thailand aged 50–75 y. Enrolled n = 1740 | – | 98.4 | 98.4 |
Remes-Troche et al. 2020 [18] Mexico | – | 1 x FIT | If + | Media (unclear by whom) | Voluntary response sampling | – | – | – | x | C | – | – | 15 May 2015–15 Jan 2016 (Ads for 3 months) | Adults aged ≥50 y. Reply to ads n = 502 Eligible n = 473 | – | 85.8 | 87.5 |
Dimova et al. 2015 [19] Bulgaria | – | 1 x FIT (& 1 if +) | Fibro-C if + | Physicians (contacted people at home) | Purposive sampling | – | x | x | – | C | x | – | Jun – Sept 2013 | Health-insured, asymptomatic adults aged ≥45 y. Invited n = 600 | – | 78.8 | 75 |
Sucevaeanu et al. 2005 [20] Romania | – | 1 x FOBT 3 samples requested | If + | Media (unclear by whom) | Voluntary response sampling | – | – | – | x | C | – | – | May 2003 – Nov 2004 | Adults aged ≥50 y. Patients interested n = 1769 | – | 70.3 | 92.6 |
Scepanovic et al. 2017 [22] Serbia | – | 1 x FIT | If + | Physicians | Random sampling | x | – | – | – | CHC | – | – | Aug – Nov 2013 | Adults aged 50–74 y. Invited n = 50,894 | – | 67.8 | 69.7 |
Gholampour et al. 2018 [24] Iran | – | 1 x FOBT | If + | Unclear | Convenience sampling | (x) | – | – | – | CHC | x | 8 x session (group) | 2016–2017 | Males aged > 50 y. Participants n = 200 | – | IG: 74.0 CG: 6.0 | 100 (n = 1) |
Salimzadeh et al. 2017 [25] Iran | – | 1 x FIT | If + | Health navigators | Purposive sampling | x | x | – | x | C | x | 1 x session (individual) | Unclear | Adults aged 45–75 y. Invited n = 1438 | – | 96.0 | 60.0 |
Stool test uptake 45–65% | |||||||||||||||||
Khuhaprema et al. 2014 [15] Thailand | – | 1 x FIT | If + | CHW | Population-based | x | – | – | – | C | – | – | April 2011- Nov 2012 | Residents aged 50–65 y. Invited n = 127,301 | – | 62.9 | 71.8 |
Bankovic Lazarevic et al. 2016 [21] Serbia | – | 1 x FIT | If + | Physicians | Population- based | – | x | x | – | C | – | – | 2013–2014 (2 years) | Adults aged 50–74 y. Invited n = 99,595 | – | 62.5 | 42.1 |
Huang et al. 2014 [9] China | x | 1 x FOBT vs. 1 x FOBT & HRFQ | If + | CDC officials | Population- based | x | – | – | – | C | – | – | July 2006 – Dec 2008 | Residents aged 40–74 y. Approached n = 400,000 (unclear how many participated) | 53.2 | 45.4 vs 53.2 | 37.3 vs. 46.8 |
Stool test uptake < 45% | |||||||||||||||||
Wu et al. 2019 [7] China | x | 2 x FIT | If + | Unclear, author refers to community mobilization] | Population- based | (x) | – | – | – | C | – | – | 2 rounds (2013–2017) | Residents aged 50–79 y. Eligible n = 1,356,068 | 39.7 | 39.7 | 23.5 |
Abuadas et al. 2018 [23] Jordan | – | Suggested FOBT | Researchers | Convenience sampling | x | – | – | – | H | – | 1 x 1-h session (group) | 1st July – 3rd Nov 2015 | Adults aged 50–75 y. Participants n = 197 | – | IG: 35.7 CG: 8.1 | – | |
Li, Qian et al 2019 [6] China | x | 1 x FOBT | If + | Physician | Population- based | – | – | x | – | C | x | – | 2 rounds (2013–2016) | Residents with medical insurance aged 50–74 y. Invited n = 1,262,214 | 35.2 | 35.2 | 26.3 |
Salimzadeh et al. 2013 [26] Iran | – | Suggested FOBT | – | Research assistants | Convenience sampling | – | x | – | – | C (Health clubs) | x | 1 x 20-min Session (unclear) | July 2011-Nov 2012 | Adults aged ≥50 y. n = 360 | – | FOBT IG: 26.0 CG: 2.8 | IG: 5.0 CG: 0 |
Huang et al. 2011 [8] China | – | 1 x FOBT | – | Health workers | Cluster random sampling | x | – | – | – | C | – | Monthly lectures (group) | May 2008 – May 2010 | Residents Person-times attending lectures n = 8981 Survey completed n = 1041 | – | 24.5 | 12 |
Lin et al. 2019 [11] China | x | 2 x FIT | If + | Media/ SMS (unclear who sent) | Population-based | – | – | – | x | C | x | – | 2015–2017 | Residents aged 50–74 y. 350,581/2,283,214 residents completed 1st stage of screening | 15.4 | 14.0 | 18.9 |
Colonoscopy only | |||||||||||||||||
Garcia-Osogobio et al. 2015 [17] Mexico | – | – | 1x | Employer | Convenience sampling | – | – | x | x | WP (H) | – | – | 2009–2010 | Employees aged 40–79 y. Invited n = 600 | – | – | 16.5 |
Chen et al. 2019 [4] China | x | – | If + | Trained staff | Population- based | x | x | – | x | C | – | – | October 2012–October 2015 | Residents aged 40–69 y. Recruited n = 1,381,561 High-risk n = 182,927 | NR | – | 14.0 |