Fig. 2
From: CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis
CircCDC45 downregulation suppressed proliferation, migration and invasion of GBM cells. siRNA targeting circCDC45 was used for circCDC45 downregulation in LN229 and A172 cells. (A and B) The expression of circCDC45 was measured by qRT-PCR. (C and D) Cell proliferation was assessed by CCK-8 assay. (E) Cell proliferation was also assessed by colony formation assay. (F) The expression of Ki67 and PCNA was quantified by western blot. (G and H) Cell invasion and migration were investigated by transwell assay. *P < 0.05