Table 2 Clinicopathological characteristics of negative PLN metastasis in stage IB1-IIA2 cervical cancer patients with or without para-aortic lymphadenectomy
Variables | Unmatched | Matched | ||||
|---|---|---|---|---|---|---|
PALN unresected (n = 6947,%) | PALN Resected (n = 237,%) | P-value | PALN unresected (n = 948,%) | PALN Resected (n = 237,%) | P-value | |
Age (years) | 48.30 ± 9.773 | 47.27 ± 9.262 | 0.108 | 47.85 ± 9.597 | 47.27 ± 9.262 | 0.404 |
FIGO stage | 0.59 | 0.749 | ||||
IB1 | 4192 (60.3%) | 148 (62.4%) | 583 (61.5%) | 148 (62.4%) | ||
IB2 | 652 (9.4%) | 27 (11.4%) | 129 (13.6%) | 27 (11.4%) | ||
IIA1 | 1491 (21.5%) | 48 (20.3%) | 176 (18.6%) | 48 (20.3%) | ||
IIA2 | 399 (5.7%) | 9 (3.8%) | 48 (5.1%) | 9 (3.8%) | ||
IB | 111 (1.6%) | 2 (0.8%) | 4 (0.4%) | 2 (0.8%) | ||
IIA | 103 (1.5%) | 3 (1.3%) | 8 (0.8%) | 3 (1.3%) | ||
Tumour size | 0.7 | 0.304 | ||||
≤ 4 cm | 5683 (81.8%) | 196 (82.7%) | 759 (80.1%) | 196 (82.7%) | ||
> 4 cm | 1051 (15.1%) | 36 (15.2%) | 177 (18.7%) | 36 (15.2%) | ||
Unknown | 213 (3.1%) | 5 (2.1%) | 12 (1.3%) | 5 (2.1%) | ||
Histological type | < 0.001 | 0.798 | ||||
SCC | 6255 (90.0%) | 189 (79.7%) | 761 (80.3%) | 189 (79.7%) | ||
AC | 539 (7.8%) | 39 (16.5%) | 159 (16.8%) | 39 (16.5%) | ||
SAC | 153 (2.2%) | 9 (3.8%) | 28 (3.0%) | 9 (3.8%) | ||
Parametrial | 0.051 | 0.059 | ||||
Negative | 6886 (99.1%) | 232 (97.9%) | 941 (99.3%) | 232 (97.9%) | ||
Positive | 61 (0.9%) | 5 (2.1%) | 7 (0.7%) | 5 (2.1%) | ||
Vaginal margin | 0.142 | 0.668 | ||||
Negative | 6808 (98.0%) | 229 (96.6%) | 921 (97.2%) | 229 (96.6%) | ||
Positive | 139 (2.0%) | 8 (3.4%) | 27 (2.8%) | 8 (3.4%) | ||
LVSI | 0.603 | 0.836 | ||||
Negative | 6003 (86.4%) | 202 (85.2%) | 813 (85.8%) | 202 (85.2%) | ||
Positive | 944 (13.6%) | 35 (14.8%) | 135 (14.2%) | 35 (14.8%) | ||
Cervical invasion | 0.601 | 0.525 | ||||
≤ 1/2 | 3067 (44.1%) | 99 (41.8%) | 431 (45.5%) | 99 (41.8%) | ||
> 1/2 | 3381 (48.7%) | 123 (51.9%) | 453 (47.8%) | 123 (51.9%) | ||
Unknown | 499 (7.2%) | 15 (6.3%) | 64 (6.8%) | 15 (6.3%) | ||
POAT | 0.354 | 0.914 | ||||
Standard | 3486 (50.2%) | 106 (44.7%) | 422 (44.5%) | 106 (44.7%) | ||
Inadequate | 371 (5.3%) | 16 (6.8%) | 56 (5.9%) | 16 (6.8%) | ||
Over | 2927 (42.1%) | 110 (46.4%) | 444 (46.8%) | 110 (46.4%) | ||
Unknown | 163 (2.3%) | 5 (2.1%) | 26 (2.7%) | 5 (2.1%) | ||