Fig. 1
From: Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma
YAP and TAZ expression in human iCCA, pCCA and dCCA. Representative IHC stains for YAP, TAZ, MCM2 and Ki-67 in cohorts of CCA subgroups of iCCA (A, n = 152), dCCA (B, n = 126) and pCCA (C, n = 155). For each subtype, a representative YAP and TAZ-positive example is shown. For pCCA an additional case with nuclear YAP/TAZ is shown. Bars: 50 μm. Adjacent bar graphs illustrate the relative nuclear positivity of YAP or TAZ for the respective CCA subgroup with regard to tumor grading (white: low/no expression; light grey: intermediate expression; dark grey: high expression)