Table 4 Transcription factors of the differentially expressed MMPs

MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

4.20E-09

7.55E-08

MMP9, MMP14, MMP1

ETV4

ets variant 4

1.15E-07

1.03E-06

MMP14, MMP1, MMP2

SRF

serum response factor (c-fos serum response element-binding transcription factor)

1.72E-07

1.03E-06

MMP14, MMP2, MMP9

ETS2

v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

3.69E-07

1.35E-06

MMP1, MMP9, MMP2

STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

3.76E-07

1.35E-06

MMP9, MMP2, MMP1, MMP14

KLF8

Kruppel-like factor 8

5.65E-06

1.70E-05

MMP14, MMP9

RELA

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

7.50E-06

1.73E-05

MMP9, MMP2, MMP14, MMP1

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

7.70E-06

1.73E-05

MMP1, MMP2, MMP9, MMP14

SNAI2

snail homolog 2 (Drosophila)

1.83E-05

3.67E-05

MMP17, MMP9

NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

3.44E-05

6.20E-05

MMP1, MMP9

JUN

jun proto-oncogene

3.91E-05

6.40E-05

MMP9, MMP2, MMP1

SP1

Sp1 transcription factor

4.40E-05

6.61E-05

MMP2, MMP9, MMP11, MMP14

TWIST1

twist basic helix-loop-helix transcription factor 1

0.000119

0.000165

MMP2, MMP1

FOS

FBJ murine osteosarcoma viral oncogene homolog

0.000318

0.000409

MMP9, MMP1

PPARG

peroxisome proliferator-activated receptor gamma

0.000427

0.000512

MMP9, MMP1

TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

0.000494

0.000556

MMP2, MMP9

ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

0.000611

0.000647

MMP1, MMP9

TP53

tumor protein p53

0.0026

0.0026

MMP1, MMP2