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Table 2 The GO function enrichment analysis of MMP family members and neighboring genes (Metascape)

From: MMP1 and MMP9 are potential prognostic biomarkers and targets for uveal melanoma

GO Category Description Count % Log10(P) Log10(q)
GO:0004222 GO Molecular Functions metalloendopeptidase activity 29 39.73 −51.76 −47.41
GO:0062023 GO Cellular Components collagen-containing extracellular matrix 17 23.29 −15.20 −11.96
GO:0008236 GO Molecular Functions serine-type peptidase activity 11 15.07 −11.66 −8.46
GO:0035987 GO Biological Processes endodermal cell differentiation 7 9.59 −10.68 −7.54
GO:0070820 GO Cellular Components tertiary granule 9 12.33 −9.36 −6.33
GO:0030246 GO Molecular Functions carbohydrate binding 10 13.70 −8.74 −5.77
GO:0051045 GO Biological Processes negative regulation of membrane protein ectodomain proteolysis 4 5.48 −8.54 −5.59
GO:0005518 GO Molecular Functions collagen binding 6 8.22 −7.62 −4.78
GO:0009611 GO Biological Processes response to wounding 13 17.81 −7.55 −4.73
GO:0070006 GO Molecular Functions metalloaminopeptidase activity 4 5.48 −6.16 −3.57
GO:0005509 GO Molecular Functions calcium ion binding 10 13.70 −4.82 −2.42
GO:1901681 GO Molecular Functions sulfur compound binding 6 8.22 −4.22 −1.89
GO:0072562 GO Cellular Components blood microparticle 4 5.48 −3.24 −1.00
GO:0042698 GO Biological Processes ovulation cycle 3 4.11 −3.23 −1.00
GO:0031348 GO Biological Processes negative regulation of defense response 5 6.85 −3.22 −0.99
GO:0005788 GO Cellular Components endoplasmic reticulum lumen 5 6.85 −2.92 −0.72
GO:0051591 GO Biological Processes response to cAMP 3 4.11 −2.72 −0.56
GO:0005125 GO Molecular Functions cytokine activity 4 5.48 −2.48 −0.34
GO:0043900 GO Biological Processes regulation of multi-organism process 5 6.85 −2.25 −0.12
GO:0019838 GO Molecular Functions growth factor binding 3 4.11 −2.25 −0.12