Table 1 Adjusted odds ratios (OR), population attributable fractions (PAF) and 95% confidence intervals (CI) for HNSCC associated with tobacco, alcohol, family history of HNC, low BMI, Hr-HPV and at-risk occupations
From: Head and neck cancer risk factors in the French West Indies
Risk factor | Cases | Controls | ||||||
|---|---|---|---|---|---|---|---|---|
n | n | ORa | 95% CIa | ORb | 95% CIb | PAFb | 95% CIb | |
Tobacco smoking | ||||||||
Ever | 114 | 142 | 6.72 | (4.24–10.64) | 5.86 | (3.47–9.90) | 65.7% | (51.7–75.6) |
Never | 30 | 263 | 1 | ref | 1 | ref | 1 | ref |
Missing | 1 | 0 | ||||||
Daily alcohol | ||||||||
Ever | 96 | 112 | 4.95 | (3.24–7.58) | 3.03 | (1.85–4.95) | 44.3% | (27.3–57.3) |
Never | 49 | 293 | 1 | ref | 1 | ref | 1 | ref |
Missing | 0 | 0 | ||||||
Family history of HNC | ||||||||
Yes | 13 | 14 | 3.67 | (1.66–8.08) | 4.70 | (1.81–12.22) | 8.9% | (1.1–16.1) |
No | 108 | 387 | 1 | ref | 1 | ref | 1 | ref |
Missing | 24 | 4 | ||||||
Body mass index | ||||||||
BMI < 18.5 | 12 | 10 | 4.63 | (1.89–11.33) | 4.96 | (1.69–14.59) | 9.0% | (1.2–16.1) |
BMI ≥ 18.5 | 110 | 391 | 1 | ref | 1 | ref | 1 | ref |
Missing | 23 | 4 | ||||||
Oral HPV Status | ||||||||
Hr-HPV+ | 19 | 30 | 2.31 | (1.34–3.99) | 2.39 | (1.23–4.63) | 15.1% | (3.9–25.0) |
Hr-HPV- | 73 | 277 | 1 | ref | 1 | ref | 1 | ref |
Missing | 53 | 98 | ||||||
At-risk occupational activity | ||||||||
Ever | 56 | 87 | 2.08 | (1.37–3.17) | 2.78 | (1.66–4.66) | 24.7% | (12.1–35.5) |
Never | 89 | 318 | 1 | ref | 1 | ref | 1 | ref |
Missing | 0 | 0 | ||||||