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Table 4 OR and 95% confidence interval for risk of colorectal cancer, adenoma and colorectal cancer plus adenoma based on quartile of energy-adjusted DASH score

From: A case-control study of Dietary Approaches to Stop Hypertension (DASH) diets, colorectal cancer and adenomas among Iranian population

Dietary DASH score

Quartile1

< 20

Quartile2

21–24

Quartile3

25–28

Quartile4

> 29

P for trend

Colorectal cancer

 Women

  Case (control)

19(14)

23(23)

16(28)

5(42)

 

  Crude OR (95% CI)

1.00

0.73(0.29–1.81)

0.42(0.16–1.06)

0.08(0.02–0.27)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.76(0.29–1.97)

0.42(0.16–1.11)

0.07(0.02–0.24)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.89(0.31–2.54)

0.42(0.14–1.24)

0.07(0.02–0.26)

< 0.001

 Men

  Case (control)

37(22)

22(26)

5(40)

2(45)

 

  Crude OR (95% CI)

1.00

0.50(0.23–1.09)

0.07(0.02–0.21)

0.02(0.00–0.12)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.47(0.21–1.06)

0.06(0.02–0.18)

0.02(0.00–0.10)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.63(0.26–1.48)

0.07(0.02–0.24)

0.02(0.00–0.13)

< 0.001

 Pooled

  Case (control)

56(36)

45(49)

21(68)

7(87)

 

  Crude OR (95% CI)

1.00

0.59(0.33–1.05)

0.19 (0.10–0.37)

0.05(0.02–0.12)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.57(0.31–1.04)

0.17(0.09–0.34)

0.04 (0.01–0.10)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.69(0.36–1.31)

0.22(0.11–0.44)

0.04(0.01–0.11)

< 0.001

Adenoma

 Women

  Case (control)

25(14)

20(23)

18(28)

8(42)

 

  Crude OR (95% CI)

1.00

0.58(0.28–1.21)

0.38(0.18–0.79)

0.13(0.05–0.32)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.57(0.27–1.19)

0.32 (0.15–0.68)

0.04(0.04–0.27)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.42(0.16–1.12)

0.25(0.09–0.69)

0.06 (0.02–0.20)

< 0.001

 Men

  Case (control)

22(22)

17(26)

14(40)

6(45)

 

  Crude OR (95% CI)

1.00

0.56(0.26–1.22)

0.33(0.15–0.73)

0.11(0.04–0.30)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.65(0.27–1.53)

0.35(0.15–0.81)

0.13(0.04–0.37)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.68(0.26–1.72)

0.30 (0.11–0.80)

0.14(0.04–0.44)

< 0.001

 Pooled

  Case (control)

47(36)

37(49)

32(68)

14(87)

 

  Crude OR (95% CI)

1.00

0.57(0.37–1.06)

0.36(0.19–0.66)

0.12 (0.06–0.25)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.57(0.31–1.07)

0.30 (0.16–0.57)

0.10(0.04–0.21)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.60(0.31–1.15)

0.31 (0.16–0.61)

0.10(0.04–0.22)

< 0.001

Colorectal cancer plus Adenoma

 Women

  Case (control)

44(14)

43(23)

34(28)

13(42)

< 0.001

  Crude OR (95% CI)

1.00

0.59(0.27–1.30)

0.38(0.17–0.84)

0.09(0.04–0.23)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.55(0.24–1.24)

0.34(0.15–0.77)

0.08(0.03–0.20)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.59(0.25–1.39)

0.35(0.15–0.83)

0.07 (0.02–0.18)

 

 Men

  Case (control)

59(22)

39(26)

19(40)

8(45)

< 0.001

  Crude OR (95% CI)

1.00

0.55(0.27–1.12)

0.17(0.08–0.36)

0.06(0.02–0.16)

0.03

  Adjusted OR* (95% CI)

1.00

0.55(0.27–1.12)

0.15(0.07–0.33)

0.05(0.02–0.14)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.64(0.30–1.35)

0.16 (0.07–0.37)

0.06(0.02–0.16)

 

 Pooled

  Case (control)

103(36)

82(49)

53(68)

21(87)

< 0.001

  Crude OR (95% CI)

1.00

0.58(0.34–0.98)

0.27(0.16–0.45)

0.08 (0.04–0.15)

< 0.001

  Adjusted OR* (95% CI)

1.00

0.56(0.33–0.95)

0.24 (0.14–0.41)

0.07(0.03–0.13)

< 0.001

  Adjusted OR**(95% CI)

1.00

0.64(0.37–1.10)

0.26 (0.10–0.47)

0.07(0.03–0.14)

 
  1. *Model 1: Adjusted for age (year)
  2. **Model 2: Adjusted for BMI (kg/m2), age (year), alcohol consumption, physical activity (MET), history of diabetes, CHD and hypertension, family history of cancer