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Table 2 Clinical and reproductive characteristics by BMI quartile among breast cancer cases and controls

From: Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study

Study characteristics

1st quartile:

BMI ≤ 22.5

N = 177

2nd quartile:

BMI > 22.5 - ≤ 25.6

N = 181

3rd quartile:

BMI > 25.6 - ≤ 29.8

N = 174

4th quartile:

BMI > 29.8

N = 173

P-value

Case status

    

.10

 Case

117 (66.1%)

110 (60.8%)

99 (56.9%)

93 (53.8%)

 

 Control

60 (33.9%)

71 (39.2%)

75 (43.1%)

80 (46.2%)

 

Demographics

 Age (years)a

46.0 (37.0, 55.0)

48.0 (40.0, 58.0)

47.5 (41.0, 56.0)

52.0 (44.0, 59.0)

< .001

Clinical characteristics

 Height, cm a

161.0 (156.0, 164.5)

160.0 (156.0, 164.0)

160.0 (155.0, 163.8)

160.0 (156.0, 164.1)

.69

 Weight, kg a

52.0 (48.5, 55.0)

62.0 (58.0, 64.9)

70.9 (66.0, 74.8)

85.9 (80.0, 94.0)

< .001

 High blood pressure at enrollment

32 (18.1)

68 (37.6)

65 (37.4)

64 (37.0)

< .001

 Systolic BP a

121.7 (109.3, 132.0)

127.0 (114.7, 145.7)

129.0 (116.7, 147.7)

132.0 (119.7, 148.7)

< .001

 Diastolic BP a

76.0 (66.7, 84.0)

78.3 (68.7, 89.3)

79.2 (72.3, 88.3)

80.3 (74.7, 89.7)

< .001

 Prior diabetes diagnosis

    

.21

  Yes

7 (4.0%)

15 (8.3%)

11 (6.3%)

16 (9.3%)

 

  No

159 (89.8%)

156 (86.2%)

143 (82.2%)

143 (82.7%)

 

  Missing

11 (6.2%)

10 (5.5%)

20 (11.5%)

14 (8.1%)

 

 Prior hypertension diagnosis

32 (21.6%)

41 (28.5%)

55 (37.2%)

65 (48.1%)

< .001

Reproductive history

 Age at menarche a

15.0 (14.0, 16.0)

15.0 (14.0, 16.0)

15.0 (14.0, 16.0)

15.0 (14.0, 17.0)

.54

 Ever pregnant

161 (91.0%)

170 (93.9)

166 (95.4)

171 (98.8)

.01

 Number of pregnancies a,b

4.0 (3.0, 6.0)

4.0 (3.0, 6.0)

4.0 (3.0, 6.0)

5.0 (4.0, 6.0)

.15

 Number of births a,b

3.0 (2.0, 5.0)

4.0 (3.0, 5.0)

4.0 (2.0, 5.0)

4.0 (3.0, 5.0)

.13

 Menopausal status

    

.06

  Pre- or peri-menopause

97 (54.8%)

87 (48.1%)

86 (49.4%)

70 (40.5%)

 

  Post-menopause

80 (45.2%)

94 (51.9%)

88 (50.6%)

103 (59.5%)

 

 Ever used HRT

    

.009

  Yes

4 (2.3%)

10 (5.5%)

11 (6.3%)

19 (11.0%)

 

  No

159 (89.8%)

153 (84.5%)

152 (87.4%)

141 (81.5%)

 

  Missing

14 (7.9%)

18 (9.9%)

11 (6.3%)

13 (7.5%)

 
  1. Where applicable, missing values were not used to generate the p-value
  2. aMedian, (Q1, Q3)
  3. bAmong those who were ever pregnant
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